Vitamin D Derivative Anti Cancer API Paricalcitol Powder CAS 131918-61-1

Vitamin D Derivative Anti-Cancer API Paricalcitol Powder CAS 131918-61-1

Paricalcitol is a synthetic vitamin D analog that is used for the treatment of secondary hyperparathyroidism, a condition commonly seen in patients with chronic kidney disease. It is a selective activator of the vitamin D receptor, which is responsible for mediating the biological effects of vitamin D in the body.

Similar to calcitriol, the active form of vitamin D, paricalcitol helps regulate calcium and phosphorus levels in the body. It acts primarily in the parathyroid glands, where it suppresses the production and secretion of parathyroid hormone (PTH). Elevated PTH levels are characteristic of secondary hyperparathyroidism and can lead to imbalances in calcium and phosphorus metabolism, resulting in bone abnormalities.

By reducing PTH synthesis and secretion, paricalcitol helps to normalize the levels of calcium and phosphorus, promoting bone health and preventing the development of renal osteodystrophy. It also aids in the absorption of calcium from the intestines and its reabsorption in the kidneys.

Paricalcitol is typically administered orally or via injection and is available as a prescription medication. It is commonly used in the management of secondary hyperparathyroidism in patients with chronic kidney disease who are undergoing dialysis or have impaired kidney function. The dosage and duration of treatment are determined by healthcare professionals based on the individual patient's needs and response to therapy.

It's important to note that the information provided here is a general overview and should not replace the advice and guidance of a healthcare professional.

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