High Purity Pesticide Intermediate Chlortalidone Thalitone Diuretic CAS 77-36-1

Factory Supply High Purity Chlortalidone / Thalitone CAS 77-36-1

Function and Application of Chlortalidone CAS 77-36-1

1. Chlorthalidone is used as a diuretic; antihypertensive.
2. Antihypertensive Agents,Diuretics,Sodium Chloride Symporter Inhibitors
3. In terms of activity, chlorothalidone is very similar to benzothiadiazide (21.3.13) and is used as an independent drug or in combination with other antihypertensive agents for lowering arterial blood pressure, and also as an adjuvant drug for treating edema caused by cardiac insufficiency and renal irregularities, including nephrotic syndrome.

Chlorthalidone is a diuretic drug used to treat hypertension. It is described as a thiazide diuretic. Compared with other medications of the thiazide class, chlortalidone has the longest duration of action but a similar diuretic effect at therapeutic doses. Chlortalidone is often used in the management of hypertension and edema. Chlorthalidone directly inhibits sodium and chloride reabsorption on the luminal membrane of the early segment in the distal convoluted tubule in the kidney. This leads to an increase in sodium, chloride, bicarbonate, and potassium secretion resulting in the excretion of water.

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